منابع مشابه
O-17: Human Ovarian Tissue Xenotransplantation Application in Drug Discover
Background: Reproductive toxicity studies (RTS) represent an important part of pre-clinical safety evaluation of any drug development process for human consumption. It is mandatory requirement that RTS must be completed before any drug can be administered to women of childbearing age. Therefore, at first segment of toxicity check the toxic effect of the drug on fertility must be tested on non-c...
متن کاملTissue banking
In the United States, organ and tissue procurement has been organized in such a way so as to maximize availability in an efficient fashion that is fair to both donor and recipient. There is a growing cooperation between organ procurement organizations (OPOs) and tissue recovery organizations to facilitate meeting the requirements of both organ and tissue procurement. Successful tissue preservat...
متن کاملOvarian tissue banking for cancer patients: fertility preservation, not just ovarian cryopreservation.
While ovarian tissue cryopreservation has commonly been equated with fertility preservation in cancer patients, there is a range of alternative options to preserve fertility. Based on the type and timing of chemotherapy, the type of cancer, the patient's age and the partner status, a different strategy of fertility preservation may be needed. If the patient has a partner or accepts donor sperm,...
متن کاملO-5: Endocrinological and Morphological Evaluation of Vitrified-Warmed Ovarian Tissue
Background: Our aim was to evaluate the recovery rate of ovarian function and the activity of hypothalamus-hypophiseal- gonadal axis following transplantation of vitrified ovaries. Materials and Methods: Five weeks-old female Wistar Rats were distributed randomly in two experimental groups; Fresh Transplanted, Vitrified-Transplanted and 8 weeks-old female Wistar rats were considered as control ...
متن کاملO-22: Bioenergy/Oxidative Status of Human Ovarian Tissue Cryopreserved by Slow Freezin or Vitrification
Background Ovarian tissue cryopreservation represents a promising strategy to preserve the ovarian function in cancer patients. It is usually performed by slow freezing/rapid thawing (SF/RT). Recent studies emphasize an ultrarapid cryopreservation procedure, vitrification/warming (V/W), since it might prevent damages due to ice crystal formation. Comparative studies between the cryopreservation...
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ژورنال
عنوان ژورنال: Human Reproduction
سال: 1997
ISSN: 1460-2350,0268-1161
DOI: 10.1093/humrep/12.suppl_2.9